Hikma Pharmaceuticals - PharmaKB

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Company ReportsHikma Pharmaceuticals

Hikma Pharmaceuticals

Hikma Pharmaceuticals plc is a British multinational pharmaceutical company with headquarters in London, UK that manufactures non-branded generic and in-licensed pharmaceutical products. It was founded by Samih Darwazah in Amman, Jordan in 1978. It is listed on the London Stock Exchange and is a constituent of the FTSE 250 Index.

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Financial

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Abiraterone	Abiraterone	2018-10-31	2027-2038	Prostatic neoplasms , Castration-resistant prostatic neoplasms , Ovarian neoplasms , Fallopian tube neoplasms , Peritoneal neoplasms
Acarbose	Acarbose	2008-05-07		Type 2 diabetes mellitus
Acetaminophen	Acetaminophen	2016-06-13	2025-2039	Pain , Fever , Cough , Postoperative pain , Obstructive lung diseases , Headache , Fatigue , Apnea , Rheumatoid arthritis , Inflammation , Osteoarthritis , Rheumatic fever , Gout , Juvenile arthritis , Menorrhagia , Ankylosing spondylitis , Bursitis , Dysmenorrhea , Premenstrual syndrome , Sinusitis , Asthma , Common cold , Allergic rhinitis perennial , Urticaria , Angioedema
Acetazolamide	Acetazolamide	1995-02-28		Altitude sickness, Glaucoma, Seizures
Acyclovir	Acyclovir	2005-06-07	2027-2030	Herpes zoster, Epstein-barr virus infections, Herpes simplex, Herpes labialis, Herpes simplex encephalitis, Aids-related opportunistic infections, Herpes genitalis, Chickenpox, Herpes zoster ophthalmicus, Shock, Ulcerative colitis, Pruritus ani, Inflammation, Adrenal insufficiency, Rheumatic diseases, Status asthmaticus, Contact dermatitis, Facial dermatoses, Hemorrhoids, Congenital adrenal hyperplasia, Foot dermatoses, Hand dermatoses, Scalp dermatoses, Leg dermatoses
Adenosine	Adenosine	2004-06-16		—
Alendronate	Alendronate	2013-02-25	2031	Postmenopausal osteoporosis, Extramammary paget disease, Chronic kidney failure, Cardiovascular diseases, Psoriasis, Lung neoplasms, Crohn disease, Skin neoplasms, Familial hypophosphatemic rickets, Osteoporosis, Hypoparathyroidism
Allopurinol	Allopurinol	2004-08-26	2025-2032	Hyperuricemia, Gout
Alosetron	Alosetron	2015-05-04		Irritable bowel syndrome, Diarrhea, Abdominal pain
Alprazolam	Alprazolam	1993-10-31		Panic disorder, Depressive disorder, Agoraphobia
Alprostadil	Alprostadil	1998-01-20		Pulmonary hypertension, Tetralogy of fallot, Patent ductus arteriosus, Aortic coarctation, Vasculogenic impotence, Tricuspid atresia, Pulmonary valve stenosis, Hypoplastic left heart syndrome, Aortic arch syndromes

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Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

hodgkin disease

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

castration-resistant prostatic neoplasms

,

,

plasma cell neoplasms

,

,

papillary thyroid cancer

,

,

,

,

promyelocytic leukemia acute

,

macular degeneration

,

choroidal neovascularization

,

pathologic neovascularization

,

,

thymus neoplasms

,

,

,

sezary syndrome

,

b-cell lymphoma marginal zone

,

prolymphocytic leukemia

,

follicular lymphoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

adult t-cell leukemia-lymphoma

,

hairy cell leukemia

,

intraocular lymphoma

,

t-cell lymphoma cutaneous

,

neutrophilic leukemia chronic

,

burkitt lymphoma

,

plasmablastic lymphoma

,

immunoglobulin light-chain amyloidosis

,

paraproteinemias

,

large granular lymphocytic leukemia

,

large-cell lymphoma immunoblastic

,

t-cell leukemia

,

,

,

aids-related lymphoma

,

monoclonal gammopathy of undetermined significance

,

respiratory aspiration

,

squamous cell carcinoma of head and neck

,

blood platelet disorders

,

,

bone marrow failure disorders

,

congenital bone marrow failure syndromes

,

disease susceptibility

,

,

,

,

myeloid leukemia acute

,

,

neoplasm metastasis

,

prostatic neoplasms

,

hypereosinophilic syndrome

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

systemic scleroderma

,

diffuse scleroderma

,

primary myelofibrosis

,

non-small-cell lung carcinoma

,

ovarian neoplasms

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

myelodysplastic syndromes

,

ovarian epithelial carcinoma

,

aggressive fibromatosis

,

myeloproliferative disorders

,

,

renal cell carcinoma

,

,

polycythemia vera

,

,

small cell lung carcinoma

,

dermatofibrosarcoma

,

pancreatic neoplasms

,

b-cell chronic lymphocytic leukemia

,

colorectal neoplasms

,

stomach neoplasms

,

head and neck neoplasms

,

,

,

plexiform neurofibroma

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

myelomonocytic leukemia acute

,

multiple myeloma

,

,

kidney neoplasms

,

thyroid neoplasms

,

thyroid diseases

,

colonic neoplasms

,

malignant mesothelioma

,

,

brain neoplasms

,

pulmonary hypertension

,

acute lung injury

,

,

chronic disease

,

desmoplastic small round cell tumor

,

urologic neoplasms

,

,

urogenital neoplasms

,

,

stem cell transplantation

,

squamous cell carcinoma

,

synovial sarcoma

,

sickle cell anemia

,

respiratory distress syndrome

,

newborn respiratory distress syndrome

,

pulmonary edema

,

falciparum malaria

,

wounds and injuries

,

cutaneous malignant melanoma

,

,

large-cell lymphoma anaplastic

,

localized scleroderma

,

eosinophilic leukemia acute

,

,

t-cell lymphoma

,

,

benign fibrous histiocytoma

,

,

malignant fibrous histiocytoma

,

,

,

primitive neuroectodermal tumors peripheral

,

essential thrombocythemia

,

,

gastrointestinal diseases

,

digestive system diseases

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

pulmonary vein stenosis

,

pathologic constriction

,

pulmonary veno-occlusive disease

,

second primary neoplasms

,

germ cell and embryonal neoplasms

,

testicular neoplasms

,

,

,

,

thrombocytopenia

,

,

thoracic neoplasms

,

squamous cell neoplasms

,

lymphangioleiomyomatosis

,

biphenotypic leukemia acute

,

solitary fibrous tumors

,

hemangiopericytoma

,

severe acute respiratory syndrome-related coronavirus

,

drug-related side effects and adverse reactions

,

maximum tolerated dose

,

recreational drug use

,

,

multiple sclerosis

,

,

,

,

,

spinal cord injuries

,

diabetes mellitus

,

type 1 diabetes mellitus

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

cholangiocarcinoma

,

,

,

uterine neoplasms

,

serous cystadenocarcinoma

,

hypersensitivity

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

pleural effusion

,

malignant pleural effusion

,

,

,

,

adenoid cystic carcinoma

,

autonomic nervous system diseases

,

,

rheumatoid arthritis

,

,

,

,

mullerian mixed tumor

,

merkel cell carcinoma

,

neuroendocrine carcinoma

,

oligodendroglioma

,

salivary gland neoplasms

,

male breast neoplasms

,

bone marrow neoplasms

,

rectal neoplasms

,

fallopian tube neoplasms

,

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

endometrial neoplasms

,

intestinal neoplasms

,

neoadjuvant therapy

,

disease progression

,

progression-free survival

,

liver cirrhosis

,

,

neoplasms by histologic type

,

connective and soft tissue neoplasms

,

connective tissue neoplasms

,

,

,

,

,

microcirculation

,

,

,

,

myeloid leukemia accelerated phase

,

,

,

pulmonary arterial hypertension

,

,

familial primary pulmonary hypertension

,

non-hodgkin lymphoma

,

graft vs host disease

,

residual neoplasm

,

,

hematologic diseases

,

bronchiolitis obliterans syndrome

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

hematopoietic stem cell transplantation

,

,

nephrogenic fibrosing dermopathy

,

,

ischemic stroke

,

,

,

cerebral infarction

,

,

,

bone marrow diseases

,

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

gastrointestinal stromal tumors

,

precursor cell lymphoblastic leukemia-lymphoma

,

myeloid leukemia chronic-phase

,

lymphoid leukemia

,

philadelphia chromosome

,

,

,

breast neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

hematologic neoplasms

,

,

systemic mastocytosis

,

respiratory tract diseases

,

,

congenital abnormalities

,

chromosome aberrations

,

chromosome disorders

,

respiration disorders

,

post-acute covid-19 syndrome

,

renal insufficiency

,

mouth neoplasms

,

,

disease-free survival

,

germ-line mutation

,

mental disorders

,

triple negative breast neoplasms

,

liver neoplasms

,

chronic renal insufficiency

,

kidney diseases

Imatinib mesylate

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

alzheimer disease

,

myeloid leukemia acute

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

rectal neoplasms

,

,

neoplasm metastasis

,

esophageal neoplasms

,

pancreatic neoplasms

,

disease progression

,

liver neoplasms

,

non-hodgkin lymphoma

,

kidney diseases

,

kidney transplantation

,

,

hepatocellular carcinoma

,

follicular lymphoma

,

triple negative breast neoplasms

,

,

stomach neoplasms

,

chronic hepatitis c

,

colonic neoplasms

,

multiple sclerosis

,

,

malignant mesothelioma

,

,

breast neoplasms

,

,

macular degeneration

,

,

liver cirrhosis

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

juvenile arthritis

,

head and neck neoplasms

,

respiratory tract diseases

,

germ cell and embryonal neoplasms

,

small cell lung carcinoma

,

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

bronchial diseases

,

neoplasms by histologic type

,

neoplasms by site

,

nerve tissue neoplasms

,

huntington disease

,

geographic atrophy

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

systemic lupus erythematosus

,

ulcerative colitis

,

,

,

,

rheumatoid arthritis

,

non-small-cell lung carcinoma

,

colorectal neoplasms

,

,

,

,

,

,

,

communicable diseases

,

adenocarcinoma of lung

,

,

,

,

febrile neutropenia

,

,

,

cytomegalovirus infections

,

type 1 diabetes mellitus

,

,

diabetes mellitus

,

human influenza

,

,

,

chronic hepatitis b

,

,

,

retinal vein occlusion

,

cardiovascular diseases

,

,

endometrial neoplasms

,

uterine hemorrhage

,

,

graft vs host disease

,

hematopoietic stem cell transplantation

,

,

respiratory syncytial virus infections

,

,

cognitive dysfunction

,

aortic valve stenosis

,

transcatheter aortic valve replacement

,

aortic valve insufficiency

,

mitral valve insufficiency

,

tricuspid valve insufficiency

Leucovorin calcium

,

promyelocytic leukemia acute

healthy volunteers/patients

,

renal cell carcinoma

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

,

uterine cervical neoplasms

,

,

chronic hepatitis d

,

,

rheumatoid arthritis

,

,

,

,

,

chronic hepatitis c

,

chronic hepatitis

,

,

allergic rhinitis

,

,

allergic conjunctivitis

,

liver neoplasms

,

atopic dermatitis

,

,

healthy volunteers/patients

,

,

,

,

,

prostatic neoplasms

,

postoperative nausea and vomiting

,

,

brain neoplasms

,

second primary neoplasms

,

,

treatment-resistant depressive disorder

,

depressive disorder

,

esophageal neoplasms

,

esophageal squamous cell carcinoma

,

hematologic neoplasms

,

,

pseudomonas infections

,

pseudomonas aeruginosa

,

,

renal cell carcinoma

,

liver cirrhosis

,

experimental liver cirrhosis

,

chronic obstructive pulmonary disease

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

ovarian epithelial carcinoma

,

,

colorectal neoplasms

,

pancreatic ductal carcinoma

,

gastrointestinal neoplasms

,

biliary tract neoplasms

,

non-small-cell lung carcinoma

,

,

,

,

acquired immunodeficiency syndrome

,

ovarian neoplasms

,

breast neoplasms

,

,

hepatocellular carcinoma

,

,

immunologic deficiency syndromes

,

,

antibiotic prophylaxis

,

,

chronic hepatitis b

,

uterine cervical neoplasms

,

condylomata acuminata

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

cystic fibrosis

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

endometrial neoplasms

,

,

triple negative breast neoplasms

,

,

chronic hepatitis c

,

,

,

,

,

neuromuscular blockade

,

chronic kidney failure

,

kidney diseases

,

chronic hepatitis

,

,

intestinal diseases

,

non-hodgkin lymphoma

,

,

,

traumatic brain injuries

,

brain concussion

,

,

post-concussion syndrome

renal cell carcinoma

,

human influenza

,

nutritional status

,

pneumococcal infections

,

pneumococcal pneumonia

,

,

,

systemic lupus erythematosus

,

cutaneous lupus erythematosus

,

inflammatory bowel diseases

,

,

,

tendon injuries

,

,

haemophilus influenzae

,

streptococcus pneumoniae

,

,

,

,

energy metabolism

,

endometrial neoplasms

,

,

mullerian mixed tumor

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

,

,

falciparum malaria

,

ovarian neoplasms

,

brain neoplasms

,

healthy volunteers/patients

,

prostatic neoplasms

,

,

,

colorectal neoplasms

,

squamous cell carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

ovarian epithelial carcinoma

,

cutaneous malignant melanoma

,

,

type 1 diabetes mellitus

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

sickle cell anemia

,

myeloid leukemia acute

,

myeloid leukemia

,

,

,

chronic hepatitis b

,

,

primary myelofibrosis

,

hepatocellular carcinoma

,

liver neoplasms

,

fallopian tube neoplasms

,

pancreatic neoplasms

,

,

hematologic neoplasms

,

ductal carcinoma

,

circulating neoplastic cells

,

uterine neoplasms

,

uterine cervical neoplasms

,

,

streptococcus agalactiae

,

,

follicular lymphoma

,

neisseria meningitidis

,

haemophilus influenzae type b

,

invasive hydatidiform mole

,

biliary tract neoplasms

,

uveal neoplasms

,

respiratory tract diseases

,

respiration disorders

,

,

focal segmental glomerulosclerosis

,

cytomegalovirus infections

,

chronic hepatitis

,

kidney diseases

,

membranous glomerulonephritis

,

nephrotic syndrome

,

,

,

endometrioid carcinoma

,

breast diseases

,

squamous cell neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

,

pulmonary tuberculosis

,

adenocarcinoma of lung

,

disease progression

,

peritoneal neoplasms

,

,

beta-thalassemia

,

,

sickle cell trait

,

essential thrombocythemia

,

polycythemia vera

,

,

,

,

,

breast neoplasms

,

,

rheumatoid arthritis

,

,

head and neck neoplasms

,

inflammatory breast neoplasms

,

,

respiratory syncytial virus infections

,

,

bacterial infections

,

,

streptococcal infections

,

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

infectious skin diseases

,

bacterial skin diseases

,

ductal carcinoma breast

,

renal insufficiency

,

,

,

,

urinary bladder neoplasms

,

acute coronary syndrome

,

,

rotavirus infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

respiratory syncytial viruses

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

acquired immunodeficiency syndrome

,

,

chronic obstructive pulmonary disease

,

communicable diseases

,

,

obstructive lung diseases

,

,

dental focal infection

,

focal infection

,

,

,

immunologic deficiency syndromes

,

ventilator-associated pneumonia

,

growth and development

,

immunologic tests

,

,

alzheimer disease

,

wasting syndrome

,

,

,

insulin resistance

,

abdominal obesity

,

lipid metabolism

,

latent autoimmune diabetes in adults

,

community-acquired infections

,

,

,

staphylococcal infections

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

clostridioides difficile

,

iron-deficiency anemia

,

deficiency diseases

,

iron deficiencies

healthy volunteers/patients

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

bcr-abl positive chronic myelogenous leukemia

,

gastrointestinal stromal tumors

,

myeloid leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

myeloid leukemia chronic-phase

,

philadelphia chromosome

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia

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